Mexico City
Most hotels near Museo Templo Mayor sit in Mexico City itself, within a short walk of the museum and the Zócalo. Hotel Templo Mayor is 170 m away and Viajero CDMX Centro Hostel 180 m, both a 3-minute walk. Hotel Amigo Suites and Hotel Azores are also close, at 340 m and 370 m. This is the practical choice if the museum is the reason for your trip: you can reach it on foot before the crowds build, and return to your room easily during an afternoon rain burst.
Cuauhtemoc
Cuauhtemoc is the other area with hotels near Museo Templo Mayor. Hostel Mundo Joven Catedral, 360 m from the museum and a 5-minute walk, and Umbral a Curio Collection by Hilton, 700 m and a 10-minute walk, both stand here. Staying in Cuauhtemoc keeps you in the same historic centre while placing you a little further from the museum entrance. Traffic is heavy in this part of Mexico City, so a location you can walk from is worth having, and the site_text suggests ordering taxis through an app at night rather than hailing them.